Sickle cell anemia seems to have targeted a certain race. About 98% of the affected people are African American. Researchers believe that the reason why African Americans are affected the most is because of the Malaria epidemic that occurs in Africa. It is believed that long ago, people who were infected with Malaria had developed the odd formation of their RBCs. Generations later, people who carry that trait can develop the disease by becoming infected with Malaria. Other races include Caucasian, Mediterranean, and Middle Eastern.
Sickle cell anemia doesn't target a certain age group. Each age group is affected equally because this disease is hereditary; meaning you are born with it. You can only recieve the disease if both your parents have the sickle cell trait.
Along with the ages, genders are both equally affected by Sickle cell anemia. Males and Females are affected equally because they are Autosomal when it comes to the disease. Autosomal means that the Sickle cell gene is on one of the first 22 chromosomes that do not determine gender.